Dapagliflozin CAS 461432-26-8 with Safe delivery

Boiling point 609.0±55.0 °C(Predicted)
density 1.349
storage temp. Sealed in dry,2-8°C
pka 13.23±0.70(Predicted)

Categories:

Product Name: Dapagliflozin
CAS No.: 461432-26-8
LogP: 2.3
Molecular Formula: C21H25ClO6
PSA: 99.4
Molecular Weight: 408.875
Exact Mass: 408.133972
EINECS: 1592732-453-0
InChIKeys: JVHXJTBJCFBINQ-ADAARDCZSA-N
H-bond Acceptor: 6
H-bond Donor: 4
SP3: 0.43
Categories: Inhibitor Drugs

Application & Function

Dapagliflozin works through inhibiting sodium-glucose transporter 2 (SGLT2), a protein in the kidney that reabsorbs glucose into the bloodstream.The use of this drug requires patients with normal renal function while patients of moderate to severe renal insufficiency should be disabled to use this drug. Single application of this product or combination with metformin, pioglitazone, glimepiride and other drugs can significantly reduce the HbA1c and fasting blood glucose of patients suffering type II diabetes. The frequency of the adverse reaction was similar to placebo with low risk of hypoglycemia, being able to reduce body weight.