Product Name: TB500
Synonyms: TB500 fragment;L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-;Thymosin Beta 4 Peptide Peptides Tb500 2mg/Vials 5mg/Vials;TB500 fragment acetate
TB-500 is a synthetic peptide of the naturally occuring healing protein present in about all human and mammalian cells known as Thymosin Beta 4 (TB4). TB 500 is thought to have beneficial effects on wound healing, injury recovery, flexibility, and inflammation. Research indicated the effects of TB 500 are on blood cell and blood vessel development, cellular differentiation, and cell migration. The healing capability is due in large from the peptide’s regulation of actin, a cell building protein essential to healing and wound repair.
Thymosin beta-4 (Thymosin-β4) is a major cellular constituent in many tissues, and its intracellular concentration may reach as high as 0.5 mM. In humans, it is encoded by the TMSB4X gene and consists of 43 amino acids, its sequence is SDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES and has a molecular weight of 4921 g/mol. Extracellular Thymosin beta-4 may contribute to physiological processes such as angiogenesis, wound healing, and regulation of inflammation. After an injury (as the first gene) Thymosin beta-4 is released by platelets and numerous other types of cells to protect the most damaged cells and tissues and to reduce inflammation and microbial growth.