Product Name: Ropivacaine hydrochloride
CAS: 132112-35-7
MF: C17H26N2O.ClH.H2O
MW: 328.88
Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (-)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (-)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (-)- and (±)-bupivacaine (Item No. 16618). Formulations containing (-)-ropivacaine have been used as local anesthetics during surgery and childbirth.
