● CAS:82186-77-4
● Color: Yellow powder
● EINECS No.:617-303-4
● MF:C30H32Cl3NO
● Purity: 99%
● Application:pharmaceutical intermediates.
Top quality Lumefantrine 82186-77-4
Product Description
Lumefantrine (benflumetol) is created for our class of drug mefloquine on Plasmodium vivax sexual and asexual body a clear killing effect on P. vivax has a good effect to prevent.
Certification of Analysis
| Identification | |
| A. color reaction | A violet color is produced |
| B. UV | Max at 234nm,266nm,301nm and 335nm |
| C. IR | Infrared absorption spectrum of test and standard (or infrared reference spectra No.76) are concordant |
| Tests | |
| chlorides | not more pronounced(0.01%) |
| related substances(TLC) | any spot obtained with test solution,other than the principal spot, is not more than four, and the color is not more than intense than the principal spot obtained with reference solution |
| loss on drying | 0.11% |
| residue on ignition | 0.13% |
| heavy metals(TLC) | <20PPM |
| Assay | 99.1% |
| Related substance(HPLC) | single impurity <0.5% total impurity <2.0% |
Function&Application
Lumefantrine belongs to the aromatic ring of methanol, actually and quinine, mefloquine belong to the same category, is the initiative of antimalarial drugs, chemical called beta 2, tsuen wan, n-butyl amine [2, 7, 9 – dichloro – to – chlorobenzene methylene – 4 – a + d – ethanol]. Experimental animal efficacy trials show that it has good antimalarial action, but to chloroquine is still showed cross resistance. Experiments show that this product is used in the treatment of falciparum malaria take orally, has the characteristics of high curative effect and side effect is small.Is recommended as a new drug for the treatment of falciparum malaria.
Indications: Lumefantrine is mainly used for the treatment of drug-resistant plasmodium falciparum.
